Scientists at MIT and other research organizations are testing chip technologies that could help bring eyesight to individuals with conditions like age-related macular degeneration and retinitis pigmentosa.

Microchips place onto or inside the eyeball are assisted by a pair of electronic glasses the patient wears. Results vary, but many subjects report significant improvement in orientation and mobility. MIT hopes to have a device within two years so that they can get FDA approval from for use on chronic patients.

See information on macular degeneration, nutrition and health.

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The restoration process starts with an image captured by a small camera attached to a pair of glasses. After streaming through a video processor, the data is then transferred back through the glasses to a tiny electrode “sheet” implanted on the retina. These electrodes use electrical impulses to communicate visual information to undamaged retinal tissue (just as healthy rods and cones would have done). The result is some degree of sight.

Currently the devices have only 60 electrodes, compared to more than 2 million in HD televisions, so images are still rough. Researchers from Second Sight will follow project participants for the next three years to track progress. They hope to develop versions with 200 and 1000 electrodes in the future.

Editor’s Notes: Certain nutrients have been researched as helping to preserve vision for those with Retinitis Pigmentosa. For more information, go to http://www.naturaleyecare.com/diseases.asp?d_num=12

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MIT engineers have designed a retinal implant for people who have lost their vision from retinitis pigmentosa or age-related macular degeneration, two of the leading causes of blindness.

The retinal prosthesis would help restore some vision by electrically stimulating the nerve cells that normally carry visual input from the retina to the brain.

The chip would not restore normal vision but could help blind people more easily navigate a room or walk down a sidewalk. “Anything that could help them see a little better and let them identify objects and move around a room would be an enormous help,” says Shawn Kelly, a researcher in MIT’s Research Laboratory for Electronics and member of the Boston Retinal Implant Project.

Patients who received the implant would wear a pair of glasses with a camera that sends images to a microchip attached to the eyeball. The glasses also contain a coil that wirelessly transmits power to receiving coils surrounding the eyeball. When the microchip receives visual information, it activates electrodes that stimulate nerve cells in the areas of the retina corresponding to the features of the visual scene. The electrodes directly activate optical nerves that carry signals to the brain, bypassing the damaged layers of retina.

The research team, led by John Wyatt, MIT professor of electrical engineering and computer science, recently reported a new prototype that they hope to start testing in blind patients within the next three years, after some safety refinements are made. Once human trials begin and blind patients can offer feedback on what they’re seeing, the researchers will learn much more about how to configure the algorithm implemented by the chip to produce useful vision.

Source: Massachusetts Institute of Technology
See more information on the latest research on nutrition and vision.

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Fascinating work being done at Dr. William Seiple at Lighthouse International in New York City. This device uses a patch that sits on the tongue, and vibrates in differnet ways depending on what the camera mounted on the glasses picks up. With training, one can “teach” the brain to pick up visual images based on the vibration being received.

This device can an even be used by people who have been blind from birth.

For quick video on yahoo, go to http://gmy.news.yahoo.com/vid/15259030

For more information on natural ways to help preserve vision, go to www.naturaleyecare.com

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New technology may replace eye drops currently used by people suffering from glaucoma and dry-eye.

Studies have found that a majority of glaucoma patients regularly skip their eye drops, putting themselves at risk for blindness, and that even when drops are used regularly, only a small percentage of the medication tends to be absorbed into the eye.

In an article published in the July issue of Investigative Ophthalmology and Visual Science, scientists announced that they have developed a contact lens that delivers medication to the eye at a constant rate for over 4 weeks. The lenses should not affect the wearer’s vision.

The special lenses were created by dissolving a biodegradable polymer called PLGA in an organic solvent, to which medication was added. After the solvent evaporated, researchers coated the polymer film/medication mix with a hydrogel called pHEMA — the same material used to make regular contact lenses. Researchers believe they can vary the molecular weight of the polymer to change the rate of drug release as needed.

To date the researchers have only tested the diffusion properties of the lens in a lab dish, but expect to be able to test the lenses in humans within a year.

SOURCE: A Drug-Eluting Contact Lens, Ciolino, et al, Investigative Ophthalmology and Visual Science. 2009;50:3346-3352.)

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A dry eye study, shows that a group using GLA showed a significant improvement in the specific symptom of ‘dryness’ at 3 and 6 months (p <0.01) as well as significant improvement in overall lens comfort at 6 months (p<0.01). Tear meniscus height was increased in the GLA group at 6 months relative to baseline (p<0.01), although all other objective signs were unchanged

GLA (gamma-linolenic acid) is an omega-6 unsaturated fatty acid made in the human body from linoleic acid, an essential fatty acid found in vegetable oils and egg yolks. GLA has anti-inflammatory properties and can also be found in oils derived from black currant seeds and the evening primrose plant.

Several small trials testing GLA and linoleic (LA) oil in dry eye syndrome with an inflammatory component report reduced ocular surface inflammation and symptom improvement.

Related Studies:
1. Barabino, M et al. Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. Cornea 22:97–101, 2003.
2. Aragona P, et al. Systemic omega-6 essential fatty acid treatment and PGE1 tear content in Sjogren’s syndrome patients. Invest Ophthalmol Vis Sci 46:4474–9, 2005
3. Kokke KH, et al. Oral omega-6 essential fatty acid treatment in contact lens associated dry eye. Contact Lens Anterior Eye 31:141-6, 2008.
4. Macri A, et al. Effect of linoleic acid and gamma-linolenic acid on tear production, tear clearance and on the ocular surface after photorefractive keratectomy. Graefes Arch Clin Exp Ophthalmol 241: 561-6, 2003.

For more information on dry eyes and natural ways this eye condition can be helped, go to Natural Eye Care
Eye Conditions section and click on Dry Eyes.

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