A study out of Denmark shows that worries over family situations can lead to chest pains or angina. The study included over 4500 middle aged people who filled in questionnaires about their own health over a six year period.
Over the six years 9% developed angina. Problems with spouses increased the risk of developing angina by a factor of three; those who had trouble with their kids were doubly likely to develop chest pains. Issues with relations that were not as close did not seem to effect the heart. Source: http://www.theheart.org/
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