Astaxanthin is a potent carotenoid antioxidant naturally occuring in many living plants.
Ingredients per softgel:
Astaxanthin (naturally derived from Haematococcus pluvialis microalgae) 4 mg.
Lutein (naturally occurring) 40 mcg.
Vitamin A (as beta carotene) (naturally occurring) 65 i.u.
Vitamin E (d-alpha tocopherol) 50 i.u.
Other ingredients: rosemary liquid extract, high oleic safflower oil, gelatin
Active Ingredients: Astaxanthin, High Oleic Sunflower Seed Oil, Vitamin E, Vitamin E (d-alpha tocopherol)
Inactive Ingredients: Gelatin
Dietary Considerations: Wheat Free, Dairy/ Milk Free, Gluten Free, Soy Free, Sugar Free, Starch Free, Yeast Free, Preservative Free, Hydrogenated Oil Free, Corn Free. Free of Artificial Colors/Flavors.
1-3 capsules per day, with meals.
Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes
The researchers pointed out that phospholipid hydroperoxides (PLOOH) accumulates abnormally in the red blood cells of patients with dementia and hypothesised that dietary carotenoids like astaxanthin might prevent this accumulation. In their research study, the scientists evaluated both astaxanthin and PLOOH levels in the red blood cells of 30 middle-aged and senior patients over the course of 12 weeks. The results suggested that supplementing with astaxanthin does in fact improved antioxidants in red blood cells and lower PLOOH levels, which may be helpful for the prevention of dementia.
Ref: Br J Nutr. 2011 Jun;105(11):1563-71. Epub 2011 Jan 31.
Astaxanthin protects neuronal cells against oxidative damage and is a potent candidate for brain food..
Another study suggested that astaxanthin be recommended as part of a treatment for cognitive brain disorders on the basis of the potential of its powerful antioxidant capacity as well as is its capacity to protect mitochondria, the energy-producing part of the cell. The researchers felt that axtaxanthin may be effective to reduce the damaging oxidation caused by free radicals that affects deterioration of brain cells and would thus be a good possibility for a natural brain food. Forum Nutr. 2009;61:129-35. Epub 2009 Apr 7.
Ina 2001, nearly 150 AMD patients were given supplements of lutein (10mg), zeaxanthin (1mg) and astaxanthin (4mg compared to others receiving a placebo). After 1 and after 2 years, the results were assessed. The patients receiving these antioxidants demonstrated significant improvement in visual acuity (ability to see more clearly). In addition, the researchers concluded that people given lutein, zeaxanthin and astaxanthin together with other nutrients were more likely to report significant improvements.
Published: Carotenoids and antioxidants in age-related maculopathy, European Journal Ophthalmology. 2012 Mar;22(2):216-225. doi: 10.5301/ejo.5000069.
A couple of randomized double blind placebo controlled pilot studies demonstrated the positive effects of supplementing with astaxanthin on visual function. In one study by Nagaki et al., (2002), it demonstrated that subjects (n=13) who received 5 mg astaxanthin per day for one month showed a 54% reduction of eye fatigue complaints.
In another study by Nakamura (2004), significant improvements were shown in reducing asthenopia and positive accommodation for the 4 mg (p<0.05) and 12 mg (p<0.01) groups. In re-evaluating the dosages in 2005 to 6 mg per day. the group improved significantly better at week 2 and 4 of the test period.
Shiratori et al., (2005) and Nagaki et al., (2006)