A 200ml bottle of Carlsons is 6.7 fluid ounces, and 1 teaspoon contains 1600 mg of Omega-3 fatty acids (800 mg of EPA and 500 mg of DHA), plus 14 mg of antioxidants to preserve freshness. The total number of teaspoons in a bottle is 40. 500ml is also available.
Omega-3 fatty acids help improve circulation, integrity of blood vessels, proper brain functioning, flexibility and permeability of cell membranes, and helps protect the retina's photoreceptor cells.
Recommended dosage is 1-2 teaspoons per day.
This fish oil is very mild and pleasant tasting with a lemony flavor.
We should mention that Carlson's uses sardines and anchovies for their oil. These fish are at the bottom of the food chain which is great. The higher on the food chain, the greater the risk of mercury, pesticide and other contaminants.
Ingredients per teaspoon 5ml
Calories (energy) 40
Calories from fat: 40
Total Fat: 4 gm
Saturated Fat: 1 gm
Polyunsaturated Fat: 2 gm
Monounsaturated Fat: 1 gm
Cholesterol: 15 mg
Vitamin E Natural (d-alpha tocopherol) 10 IU
Omega-3 Fatty Acids (from fish oil) 1600 mg
Antioxidant Blend 14 mg
EPA (Eicosapentaenoic Acid) 800 mg
DHA (Docosahexaenoic Acid) 500 mg
Other Omega-3 Fatty Acids: 300 mg
Ingredients: Omega-3 fish oil, natural lemon flavor, rosemary extract, ascorbyl palmitate, natural tocopherols.
Directions: Take one teaspoonful one or two times a day AT MEALTIME. To retain freshness after initially opening the bottle keep refrigerated and preferably use within 3 months.
A Randomized, Double-Blinded, Placebo-Controlled Study of the Effect of a Combination of Lemon Verbena Extract and Fish Oil Omega-3 Fatty Acid on Joint Management
This was a randomized, double-blind placebo-controlled study over the course of 9 weeks with the goal of testing the efficacy of an antioxidant/anti-inflammatory supplement containing standardized lemon verbena (Aloysia triphylla, Lippia citriodora) extract and fish oil omega-3 fatty acid in a human pilot trial as an alternative treatment for joint management.
The conclusion of this pilot study was that supplementation with lemon verbena combined with omega-3 fatty acids significantly reduced pain and stiffness and improved over function. This method should be considered for further investigation as a complementary and alternative treatment for improving joint status in subjects with joint discomfort.
Ref: J Altern Complement Med. 2011 November; 17(11): 1051–1063. doi: 10.1089/acm.2010.0410
Anti-inflammatory therapy in osteoarthritis including omega 3 and omega 6 fatty acids
This abstract validated a wide range of existing evidence concluding that omega 3 supplementation alleviates the progression of osteoarthritis and has exciting therapeutic potential for preventing cartilage degradation associated with chronic inflammatory in joints.
Ref: Pol Merkur Lekarski. 2012 May;32(191):329-34.
Nutritional status in relation to adipokines and oxidative stress is associated with disease activity in patients with rheumatoid arthritis
This study assessed 37 patients with RA as to whether the disease activity was associated with dietary habits, nutritional status, adipokines and oxidative stress in patients with rheumatoid arthritis.
The study concluded that supplementing with ?-3 polyunsaturated fatty acids, fish oil, and monounsaturated fatty acid seem to affect disease activity and may have beneficial effects by decreasing inflammation.
Ref: Nutrition. 2012 Nov;28(11-12):1109-14. doi: 10.1016/j.nut.2012.02.009.
Study finds significant potential for omega-3 fatty acids in the prevention and treatment of arthritis
Writing in the September, 2011 issue of the journal Osteoarthritis and Cartilage, Dr. Tarlton’s team of British researchers report the results of an animal experiment which found that omega-3 fatty acids reduced many of the signs of osteoarthritis.
The study compared the effect of a standard high omega-6 diet containing corn oil or a diet enhanced with fish oil, which is high in omega-3 fatty acids, in a breed of guinea pigs that naturally develop arthritis. An arthritis-resistant breed of guinea pigs was used as controls. The animals received the diets for 20 weeks. After this period of time, the cartilage, bone and blood factors were examined for signs of the disease.
There was strong evidence that omega-3 influenced the biochemistry of the disease. This was shown not only to help prevent disease, but also to slow its progression, potentially controlling established osteoarthritis," Dr Tarlton noted.
Diabetes / Diabetic Retinopathy
Fish oil and glycemic control in diabetes. A meta-analysis
This study was based on a meta-analysis from published clinical trials to evaluate the benefits of supplement with fish oil to lower serum triglyceride levels, as hypertriglyceridemia is associated with cardiovascular disease in diabetes.
The study conclusion was that the use of fish oil has no adverse affects on HbA1c in diabetic subjects and lowers triglyceride levels effectively by almost 30%. The study also suggested that this may be accompanied by a slight increase in LDL cholesterol concentration. The researchers concluded that fish oil may be useful in treating dyslipidemia in diabetes.
Ref: Diabetes Care. 1998 Apr;21(4):494-500.
Fish Oil & Hypertension 2012 study
The researchers wanted to evaluate the belief that fish oil is helpful in reducing blood pressure.
The study evaluated 17 studies involving more than 1500 hypertensive and normotensive subjects, and found that in 8 studies, a statistically significant reduction in systolic and diastolic blood pressure in hypertensive patients. They also found that in 9 other studies, a non-significant reduction in normal blood pressure subjects.
The researchers conclusion was that in high blood pressure patients there is a small but statistically significant benefit, but that it should not be recommended as an alternative to blood pressure lowering medication.
Ref: Researchers: Campbell F, Dickinson HO, Critchley JA, Ford GA, Bradburn M., University of Sheffield, Sheffield, UK. Published: A systematic review of fish-oil supplements for the prevention and treatment of hypertension, Eur J Prev Cardiol. 2012 Jan 30
Omega-3 Fatty Acids (2011) & Lower Risk of Macular Degeneration Omega-3 & Macular Degeneration New 2008 Study
This 10 year study reviewed the diet of nearly 40,000 women and health professionals with an average age of 54.6 years. More than 38,000 of the participants were free of AMD, measured by incident AMD and a reduction of 20/30 or worse. 235 cases of AMD were confirmed in the ten years of follow-up.
Their conclusion substantiated earlier findings that a diet that regularly including omega-3 fatty acids significantly lowered risk of age related macular degeneration in women.
Ref: Arch Ophthalmol. 2011;129(7):921-929
This study identified 274 abstracts, 3 prospective cohort, 3 case-control, and 3 cross-sectional studies.
Using quantitative methods, a high dietary intake of omega-3 fatty acids was associated with a 38% reduction in the risk of late AMD. Fish intake (2x per week) was associated with reduced risk of early and late AMD.
Ref: Arch Ophthalmol. 2008;126(6):826-833.
Prospective study of dietary fat and the risk of age-related macular degeneration -The objective of this study was to examine prospectively the association between fat intake and AMD among data collected from 567 with AMD, with a visual loss of 20/30 or more.
The study conclusion was that total fat intake was positively associated with risk of AMD onset, but that a high intake of fish may reduce the risk of AMD.
Ref: Cho E, Hung A, Willet WC, Spiegelman D, Rimm EB, Seddon JM, et al. Prospective study of dietary fat and the risk of age-related macular degeneration. Am J Clin Nutr 2001;73:209-18.
Dietary ?-3 Fatty Acid and Fish Intake and Incident Age-related Macular Degeneration in Women
The objective of this study was to examine whether intake of ?-3 fatty acids and fish affect incidence of age-related macular degeneration (AMD) in women, using questionnaires completed by 38,022 women free of a diagnosis of AMD.
The conclusion of the study was that regular consumption of DHA and EPA and fish was associated with a significantly decreased risk of incident AMD in women, and may be of benefit in primary prevention of AMD.
Ref: Arch Ophthalmol. 2011 July; 129(7): 921–929.Published online 2011 March 14. doi: 10.1001/archophthalmol.2011.34
Dietary fat and fish intake and age-related maculopathy (ARM)
The goal of this cross-sectional, urban population-based study was determine if there was an association between the intake of dietary fat and age-related maculopathy.
The study concluded that a higher frequency of fish consumption was associated with decreased odds of late ARM, though participants with higher energy-adjusted intakes of cholesterol were significantly more likely to have late ARM, with an increased risk for late ARM for the highest compared with the lowest quintile of intake.
Ref: Arch Ophthalmol. 2000 Mar;118(3):401-4.
Clinical trial of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment.
The study conclusion was that for patients with retinitis pigmentosa beginning vitamin A therapy, addition of docosahexaenoic acid, 1200 mg/d, slowed the course of disease for 2 years. Among patients on vitamin A for at least 2 years, a diet rich in omega-3 fatty acids slowed the decline in visual field sensitivity.
Ref: Arch Ophthalmol. 2004;122(9):1297-1305.
2010 Study: DHA supplementation for late onset Stargardt’s disease
This study showed some improvement in vision for those with Stargardt's Disease who supplemented with 840 mg per day of DHA (omega-3 fatty acids) for 6 months or more. DHA is the acronym for docosahexaenoic acid, an essential omega-3 fatty acid.
Ref: Authors: Giuseppe Querques, Pascale Benlian, Bernard Chanu, et al Published Date June 2010 Volume 2010:4 Pages 575 - 580 DOI: http://dx.doi.org/10.2147/OPTH.S1004