This glutathione building formula was designed by Dr. Marc Grossman to help support the health of the eye lens, and may be helpful in both preventing and/or managing cataracts.**
Although the formula as a whole has not been studied, a number of the nutrients in the formula have peer review research done related to cataractServing Size 3 capsules
Servings per container 30
Total # of capsules 90
Amount Per Serving% DV
Vitamin C (as ascorbic acid) 500 mg833%
Vitamin E (as mixed tocopherols) 200 IU667%
Riboflavin 50 mg2941%
Selenium (as l-selenomethionine) 200 mcg286%
Alpha Lipoic Acid 200 mg*
L-Glutathione Reduced (reduced) 250 mg*
N-Acetyl L-Cysteine 400 mg*
Recommended Dosage: 3 capsules per day with meals (best divided per meal).
*Daily Values not established
** These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
Study: Glutathione - Antioxidant (2000)
Glutathione, which is particularly concentrated in the lens, has been shown to have a hydroxyl radical-scavenging function in lens epithelial cells. Giblin FJ. Glutathione: a vital lens antioxidant. J Ocul Pharmacol Ther 2000 Apr; 16(2):121-35. A significantly lower level of glutathione has been found in older people (age-dependent, as well) compared to younger ones. Moreover, an increase of oxidized glutathione by-product over time suggests more oxidation and the incumbent higher risk of age-related eye diseases. Brubaker RF, et al. Ascorbic acid content of human corneal epithelium.
Invest Ophthalmol Vis Sci 2000 Jun;41(7):1681-3.
Alpha lipoic acid (1995) useful in cataract formation
Studies have shown beneficial effects of lipoic acid treatment on cataracts in rats. It may be of therapeutic use in preventing human cataracts and their associated complications. Lipoic acid has also been used to treat glaucoma. Kilic F; Handelman GJ; Serbinova E; Packer L; Trevithick JR. Modelling cortical cataractogenesis 17: in vitro effect of a-lipoic acid on glucose-induced lens membrane damage, a model of diabetic cataractogenesis.
Biochem Mol Biol Int, 1995 Oct, 37:2, 361-70
Study: N-Acetyl-Carnosine (NAC) (2001) & Cataracts
Statistical analysis revealed the significant differences over 6 and 24 months in cumulative positive changes of overall characteristics of cataracts in the NAC-treated Group II from the control Group I.The N-acetylated form of natural dipeptide L-carnosine appears to be suitable and physiologically acceptable for nonsurgical treatment for senile cataracts.
Peptides 2001 Jun;22(6):979-94
Study: Vitamin C & Cataracts 2010 Indian Study
A study published in "Archives of Ophthalmology" showed an inverse link between vitamin C and cataracts. This population-based cross-sectional analytic study measured the plasma vitamin C levels in 5638 people 60 years of age or older. They were checked for cataracts and type of cataracts. Low levels of lutein, zeaxanthin, retinol and vitamin C all showed to be correlated to cataracts. However, low vitamin C levels had by far the strongest association and were also consistent by type of cataract.
Ref: Ophthalmology. 2011;118(10):1958-1965
Study: Riboflavin (1991), vitamins C, E, carotene, niacin, thiamine & cataracts
Dietary intake of riboflavin, vitamins C, E, and carotene, niacin, and thiamine significantly decreased the risk of all cataract types. Combining the different antioxidant nutrients produced the greatest effect. Leske, et al.
Arch Ophthalmol 1991 Feb;109(2):244-51.
See more studies on cataracts.