This glutathione building formula was designed by Dr. Marc Grossman to help support the health of the eye lens, and may be helpful in both preventing and/or managing cataracts.*
Although the formula as a whole has not been studied, a number of the nutrients in the formula have peer review research done related to cataractServing Size 3 vcapsules
Amount Per Serving% DV
Vitamin C (as ascorbic acid) 500 mg833%
Vitamin E (as mixed tocopherols) 200 IU667%
Riboflavin 50 mg2941%
Selenium (as l-selenomethionine) 200 mcg286%
Alpha Lipoic Acid 200 mg*
L-Glutathione Reduced (reduced) 250 mg*
N-Acetyl L-Cysteine 400 mg*
Recommended Dosage: 3 capsules per day with meals (best divided per meal).
*Daily Values not established
** These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
Study: Glutathione - Antioxidant (2000)
Glutathione, which is particularly concentrated in the lens, has been shown to have a hydroxyl radical-scavenging function in lens epithelial cells. Giblin FJ. Glutathione: a vital lens antioxidant. J Ocul Pharmacol Ther 2000 Apr; 16(2):121-35. A significantly lower level of glutathione has been found in older people (age-dependent, as well) compared to younger ones. Moreover, an increase of oxidized glutathione by-product over time suggests more oxidation and the incumbent higher risk of age-related eye diseases. Brubaker RF, et al. Ascorbic acid content of human corneal epithelium.
Invest Ophthalmol Vis Sci 2000 Jun;41(7):1681-3.
Alpha lipoic acid (1995) useful in cataract formation
Studies have shown beneficial effects of lipoic acid treatment on cataracts in rats. It may be of therapeutic use in preventing -human cataracts and their associated complications. Lipoic acid has also been used to treat glaucoma. Kilic F; Handelman GJ; -Serbinova E; Packer L; Trevithick JR. Modelling cortical cataractogenesis 17: in vitro effect of a-lipoic acid on -glucose-induced lens membrane damage, a model of diabetic cataractogenesis.
Biochem Mol Biol Int, 1995 Oct, 37:2, 361-70
Study: N-Acetyl-Carnosine (NAC) (2001) & Cataracts
Statistical analysis revealed the significant differences over 6 and 24 months in cumulative positive changes of overall characteristics of cataracts in the NAC-treated Group II from the control Group I.The N-acetylated form of natural dipeptide L-carnosine appears to be suitable and physiologically acceptable for nonsurgical treatment for senile cataracts.
Peptides 2001 Jun;22(6):979-94
Study: Vitamin C & Cataracts 2010 Indian Study
A study published in "Archives of Ophthalmology" showed an inverse link between vitamin C and cataracts. This population-based cross-sectional analytic study measured the plasma vitamin C levels in 5638 people 60 years of age or older. They were checked for cataracts and type of cataracts. Low levels of lutein, zeaxanthin, retinol and vitamin C all showed to be correlated to cataracts. However, low vitamin C levels had by far the strongest association and were also consistent by type of cataract.
Ref: Ophthalmology. 2011;118(10):1958-1965
Study: Riboflavin (1991), vitamins C, E, carotene, niacin, thiamine & cataracts
Dietary intake of riboflavin, vitamins C, E, and carotene, niacin, and thiamine significantly decreased the risk of all cataract types. -Combining the different antioxidant nutrients produced the greatest effect. Leske, et al.
Arch Ophthalmol 1991 Feb;109(2):244-51.
See more studies on cataracts.