Study: Essential Fatty Acids, Vitamins B6 and C - Dry Eyes

D.F. Horrobin and colleagues have carried out some preliminary studies using the supplemental intake of essential fatty acids, vitamin B6 and vitamin C to treat dry eyes. The rationale for this treatment was based on the biosynthesis of prostaglandin E1 (PGE1), which is necessary for acqueous tear secretion by the lacrimal glands. Patients received 2 x 500 mg capsules of Evening Primrose Oil, 50 mg of vitamin B6 and 1 gram of Vitamin C three times daily.

The results showed that 10 of the 17 patients had substantial improvement of symptoms and Schirmer Test in 2-6 weeks, 3 patients reported improved symptoms though without improved Schirmer testing. The authors conclusion was that this treatment approach is effective in many cases.References: 1) Horrobin DF, Campbell A. McEwen CG. Treatment of the Sicca Syndrome and the Sjogren's Syndrome with E.F.A. Pyroxidine and Vitamin C. Prog Lipid Res 8(4). 263-4, 1981. 2)Horrobin DF Campbell A. Srogren's Syndrome and the Sicca Syndrome: The Role of Essential Fatty Acids and Vitamin C. Medical Hypothesis. 6: 225-232 1980.