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Search Results for: fuch

Current Genetic Eye Disease Research on Fuch’s, Leber’s and Retinitis Pigmentosa

Current research on genetic eye diseases focuses mostly on genetic therapies. Scientists have learned how to sequence DNA at a relatively low cost. New tools for modifying genetic materials, such as the CRISPR, have opened the door for new treatments and even cures. Certain eye disorders are caused by mutated genes and genetic predispositions. This … Continue reading “Current Genetic Eye Disease Research on Fuch’s, Leber’s and Retinitis Pigmentosa”

What is Fuchs’ Corneal Dystrophy?

Fuchs’ Corneal Dystrophy is named for the Austrian ophthalmologist Ernst Fuchs, who first described the condition in 1910. He described thirteen patients who suffered from corneal clouding, blisters on the corneal epithelia and loss of corneal sensation. “Dystrophy” refers to any disorder or condition in which a particular tissue or organ of the body wastes … Continue reading “What is Fuchs’ Corneal Dystrophy?”

Fuchs Corneal Dystrophy Linked to Oxidative Stress

  Fuchs dystrophy is a slowly progressing disease that occurs when endothelial cells gradually deteriorate without any apparent reason.  Eventually, it causes the cornea to swell and makes vision distorted. A study published in The American Journal of Pathology indicates that oxidative stress plays a part in the onset of Fuchs corneal dystrophy.  People affected … Continue reading “Fuchs Corneal Dystrophy Linked to Oxidative Stress”

Fuchs Corneal Dystrophy Gene Identified

Scientists have found a gene that may be responsible for the progressive eye disease Fuchs corneal dystrophy (FCD). Published in the New England Journal of Medicine, the study concludes that people with a gene called transcription factor 4 are five times more likely to develop FCD. HealthDay reports that Senior study author Albert Edwards tells … Continue reading “Fuchs Corneal Dystrophy Gene Identified”

Dry Eyes, Computer Screens, and Meibomian Gland Dysfunction (MGD)

Dry eyes are among the most prevalent issues reported by our customers and patients. Women experiencing perimenopause and menopause frequently have dry eyes. However, it is increasingly observed across all age groups, largely attributable to prolonged use of digital devices such as computers, laptops, tablets, and smartphones. 1 2 This extended screen time alters blinking … Continue reading “Dry Eyes, Computer Screens, and Meibomian Gland Dysfunction (MGD)”

Retinitis Pigmentosa Gene Editing Studied on Human Embryos

The genetic eye disease Retinitis Pigmentosa is the target of gene editing research on human embryos by Dr. Dietrich Elgi at Columbia University. National Public Radio reported on this research1 shortly after a Chinese scientist announced he had created the world’s first two gene-edited babies.2 Both scientists use the CRISPR tool to genetically modify human … Continue reading “Retinitis Pigmentosa Gene Editing Studied on Human Embryos”

Which Parts of the Eyes Are Associated with Which Eye Diseases?

The eyes are small, but they have many parts including the eyelids, sclera, cornea, lens, optic nerve and retina. We depend heavily on our vision. When something goes wrong, the eyes are disproportionately affected. For example, a senior at risk of heart disease is also at risk of an ocular arterial or vein occlusion. Also, … Continue reading “Which Parts of the Eyes Are Associated with Which Eye Diseases?”

Leber Congenital Amaurosis Gene Therapy Approved by FDA

The rare eye disease Leber Congenital Amaurosis, caused by a defective gene, has a new genetic treatment. This is the first time the US Food and Drug Administration has approved gene therapy for an inherited disease. The RPE65 gene provides a blueprint for a protein that makes light receptors work properly. Individuals with a defective … Continue reading “Leber Congenital Amaurosis Gene Therapy Approved by FDA”