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Current Genetic Eye Disease Research on Fuch’s, Leber’s and Retinitis Pigmentosa

Current research on genetic eye diseases focuses mostly on genetic therapies. Scientists have learned how to sequence DNA at a relatively low cost. New tools for modifying genetic materials, such as the CRISPR, have opened the door for new treatments and even cures. Certain eye disorders are caused by mutated genes and genetic predispositions. This … Continue reading “Current Genetic Eye Disease Research on Fuch’s, Leber’s and Retinitis Pigmentosa”

Leber Congenital Amaurosis Gene Therapy Approved by FDA

The rare eye disease Leber Congenital Amaurosis, caused by a defective gene, has a new genetic treatment. This is the first time the US Food and Drug Administration has approved gene therapy for an inherited disease. The RPE65 gene provides a blueprint for a protein that makes light receptors work properly. Individuals with a defective … Continue reading “Leber Congenital Amaurosis Gene Therapy Approved by FDA”

Gene Therapy for Leber’s Disease

In 2009, Dr. Jean Bennett and his team from Albert Maguire of the University of Pennsylvania School of Medicine injected a benign virus carrying a connected copy of an essential gene into a teenage boy’s retina. This patient had lost vision due to a genetic disorder called “Leber’s Congenital Amaurosis (LGA). The result was improved … Continue reading “Gene Therapy for Leber’s Disease”

Leber’s Disease – Gene therapy transforms eyesight

Pennsylvania researchers using gene therapy have made significant improvements in vision in 12 patients with a rare inherited visual defect, a finding that suggests it may be possible to produce similar improvements in a much larger number of patients with retinitis pigmentosa and macular degeneration.

Corneal Health: Best Ways to Help Your Eyes

The cornea plays a crucial role in our vision. It is the transparent tissue at the front of the eyeball where light enters the eye. Approximately 65% to 75% of the refraction of light occurs in the cornea. The cornea also protects against external threats and harmful UV radiation. However, this vital part of our … Continue reading “Corneal Health: Best Ways to Help Your Eyes”

Healthy Cells Mean a Healthy Body: Mitochondria Maintenance

Keeping our cells healthy is key to staying well and helping to prevent disease. Your 30 trillion cells each contain mitochondria, the cell’s tiny “battery” and energy source. The main cause of death worldwide is non-communicable diseases such as heart disease, strokes, diabetes, cancer, chronic lung diseases, and brain diseases, including Alzheimer’s disease and dementia. … Continue reading “Healthy Cells Mean a Healthy Body: Mitochondria Maintenance”

Research on Reversing Color Blindness

Approximately eight per cent of men and one-half of one per cent of women in the U.S. have a problem with their color perception. Most colorblind people have lost only part of their color vision. Usually, only one or two types of cones are either absent or not functioning normally. If the dysfunction is in … Continue reading “Research on Reversing Color Blindness”

Mitochondria: Essential Powerhouse for Brain & Vision

Why are mitochondria essential to your health and well-being? Mitochondria are the energy batteries of our cells. They are tiny organelles within most cells of the body that provide respiration and energy. Low metabolism develops in the brain as we age and is noticeable in brain regions where mitochondrial structure has changed. 1 The mitochondria … Continue reading “Mitochondria: Essential Powerhouse for Brain & Vision”

Retinitis Pigmentosa Gene Editing Studied on Human Embryos

The genetic eye disease Retinitis Pigmentosa is the target of gene editing research on human embryos by Dr. Dietrich Elgi at Columbia University. National Public Radio reported on this research1 shortly after a Chinese scientist announced he had created the world’s first two gene-edited babies.2 Both scientists use the CRISPR tool to genetically modify human … Continue reading “Retinitis Pigmentosa Gene Editing Studied on Human Embryos”

Which Parts of the Eyes Are Associated with Which Eye Diseases?

The eyes are small, but they have many parts including the eyelids, sclera, cornea, lens, optic nerve and retina. We depend heavily on our vision. When something goes wrong, the eyes are disproportionately affected. For example, a senior at risk of heart disease is also at risk of an ocular arterial or vein occlusion. Also, … Continue reading “Which Parts of the Eyes Are Associated with Which Eye Diseases?”