Low Cholesterol Linked to Lower Risk of Some Types of Prostate Cancer

A new study published in Cancer Epidemiology Biomarkers & Prevention, a journal of the American Association for Cancer Research, shows that men whose cholesterol was in a healthy range (below 200) had less than half the risk of developing high-grade prostate tumors compared to men with high cholesterol.

Researchers studied 5,586 men aged 55 and older who participated in the Prostate Cancer Prevention Trial between 1993 and 1996.  Although cholesterol levels made no difference in the odds of getting prostate cancer for most of the participants, it made a significant difference for the 60 men who developed high-grade tumors which grow and spread fast. For these men, the chance of developing an aggressive tumor was 59% lower among men with cholesterol under 200.

Although more research is planned on the topic, this study reinforces the idea that limiting fats in the bloodstream can reduce the risk of cancer.

SOURCE:  Men with Low Serum Cholesterol Have a Lower Risk of High-Grade Prostate Cancer in the Placebo Arm of the Prostate Cancer Prevention Trial, Platz, et al, Cancer Epidemiol Biomarkers Prev 2009;18(11):2807–13.