Astaxanthin (by Pure Encapsulations (Healthcare Practitioner Brand) is a potent carotenoid antioxidant naturally occuring in many living plants. Carotenoids are antioxidants that support not only overall health, but fight free radicals that damage your vision and the nervous system in general - which includes brain functioning and cognitive capacity.
Ingredients per softgel
1-3 capsules daily with meals.
The researchers pointed out that phospholipid hydroperoxides (PLOOH) accumulates abnormally in the red blood cells of patients with dementia and hypothesised that dietary carotenoids like astaxanthin might prevent this accumulation. In their research study, the scientists evaluated both astaxanthin and PLOOH levels in the red blood cells of 30 middle-aged and senior patients over the course of 12 weeks. The results suggested that supplementing with astaxanthin does in fact improved antioxidants in red blood cells and lower PLOOH levels, which may be helpful for the prevention of dementia.
Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes, British Journal Nutrition, June, 2011:1563-71.
Another study suggested that astaxanthin be recommended as part of a treatment for cognitive brain disorders on the basis of the potential of its powerful antioxidant capacity as well as is its capacity to protect mitochondria, the energy-producing part of the cell. The researchers felt that axtaxanthin may be effective to reduce the damaging oxidation caused by free radicals that affects deterioration of brain cells and would thus be a good possibility for a natural brain food. Astaxanthin protects neuronal cells against oxidative damage and is a potent candidate for brain food., Forum of Nutrition, 2009;61:129-35
In a 2001 study nearly 150 AMD patients were given supplements of lutein (10mg), zeaxanthin (1mg) and astaxanthin (4mg compared to others receiving a placebo). After 1 and after 2 years, the results were assessed. The patients receiving these antioxidants demonstrated significant improvement in visual acuity (ability to see more clearly). In addition, the researchers concluded that people given lutein, zeaxanthin and astaxanthin together with other nutrients were more likely to report significant improvements.
Carotenoids and Antioxidants in Age-related Maculopathy, European Journal of Ophthalmology. 2012 Mar;22(2):216-225.
A couple of randomized double blind placebo controlled pilot studies demonstrated the positive effects of supplementing with astaxanthin on visual functioning. In one study (Nagaki et al., 2002), it demonstrated that 13 subjects who received 5 mg astaxanthin daily for one month showed a 54% reduction of eye fatigue complaints.
In another pilot (Nakamura, 2004) significant improvements were shown in reducing asthenopia and positive accommodation for the 4 mg (p<0.05) and 12 mg (p<0.01) groups. In re-evaluating the dosages in 2005 to 6 mg per day. the group improved significantly better at week 2 and 4 of the test period.
Shiratori et al., (2005) and Nagaki et al., (2006)
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