Astaxanthin (2011) & Dementia


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Phospholipid hydroperoxides (PLOOH) is an enzyme that abnormally accumulate abnormally in the red blood cells of patients with dementia. Scientists studied whehter powerful carotenoid antioxidants could be helpful. They conducted a double-blind, random, placebo-controlled trial in 30 patients to see whether astaxathin would be helpful as a supplement. Patients were give either 6mg or 12mg of astaxanthin daily for 12 weeks. The researchers looked at astaxanthin and PLOOH levels in the elderly and middle-aged patients.

They found that astaxanthin was higher in the red blood cells (erythrocytes) of both groups who given that supplement than in the placebo group. At the same time they found that PLOOH levels decreased more strongly in the groups receiving astaxanthin. They also looked at plasma where PLOOH levels were also reduced, although less strongly.

The scientist felt that these results may indicate a valuable contribution to the prevention of dementia.

Researchers: Nakagawa K, Kiko T, Miyazawa T, Carpentero Burdeos G, Kimura F, Satoh A, Miyazawa T. Source Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan

Published: British Journal of Nutrition, June, 2011