After adjustment for the factors of age, smoking, and histories of cancer and coronary heart disease, researchers found that urinary levels of melatonin was 40% lower in AMD patients compared than that of the age-and gender-matched controls.
The researchers concluded: “The significance of this result and the role of melatonin in the occurrence of AMD require further investigation.”
Ref: Molecular Vision (Urinary 6-sulfatoxymelatonin level in age-related macular degeneration patients. Molecular Vision, 2009;15(179-80):1673-1679).
For more related studies, go to Natural Eye Care Macular Degeneration Research Studies