Vitamin D (2007) & Rheumatoid Arthritis

Learn more about treatment of rheumatoid arthritis

Researchers discovered that vitamin D receptors were contained in a variety of cells comprising the immune system (dendritic cells) and that they could produce this component. This gave rise to the suggestion that vitamin D plays a role in the regulation of the immune system.

Vitamin D is developed in the body by exposure to sunlight. Low levels of vitamin D in the blood may be due, not only to limited sunlight exposure, but genetic factors and nutrition.

Following these conclusions, researchers looked for correlations in rheumatoid arthritis patients and found that they have low blood levels of vitamin D, and that their condition is more severe in the winter when light levels are lower.

Researchers have also found that consuming greater amounts of vitamin D was correlated with marked improvement, not only in RA symptoms, but in the health of the immune system.

Researchers: Cutolo M, Otsa K, Uprus M, Paolino S, Seriolo B.

Published: Vitamin D in rheumatoid arthritis, Autoimmun Rev. 2007 Nov;7(1):59-64. Epub 2007 Aug 14.