Alpha Lipoic Acid (2011) & Diabetes

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In this study the reseachers evaluated the effectiveness and safety of alpha lipoic acid function in producting against nerve damage in diabetic patients.

The 4-year, double-blind, randomized study assessed 460 diabetic patients with mid to moderate nerve damage as a result of their diabetic condition.

The researchers found that, while ALA did not produce results in one goal of the study (NIS, NIS-LL, and 7 neurophysiologic tests), it did result in a significant improvement of nerve damage impairments and prevented further degredation. In addition it was well tolerated.

Researchers: Ziegler D, Low PA, Litchy WJ, Boulton AJ, Vinik AI, Freeman R, Samigullin R, Tritschler H, Munzel U, Maus J, Schutte K, Dyck PJ., Institute for Clinical Diabetology, German Diabetes Center at the Heinrich Heine University, Germany

Published: Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial, Diabetes Care. 2011 Sep;34(9):2054-60