Vitamin B12 (1996) & Insomnia
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Researchers evaluated results of treating 106 patients who suffered from various forms of insomnia with a combination of vitamin B12, bright light, chronotherapy and/or hypnotism. 32% of the patients experienced moderate to marked improvement. This study did not evaluate use of B12 alone, and other research has suggested that B12 alone does not bring about statistically significant improvements.
Nonetheless, since B12 supports the nervous system, it may well be that a B12 deficiency contributes to insomnia as a secondary condition.
Research: A multicenter study of sleep-wake rhythm disorders: therapeutic effects of vitamin B12, bright light therapy, chronotherapy and hypnotics., Yamadera H., et al.; Psychiatry Clin Neurosci. 1996 Aug;50(4):203-9.