Lipoic acid (1997) diabetic retinopathy

Learn more about diabetic retinopathy.


In both preliminary and double-blind trials researchers have found that 600mg to 1200mg daily alpha lipoic acid improves the symptoms of diabetic neuropathy.

Researchers: K.J. Ruhnau, et al.
Published: Effects of 3-week oral treatment with the antioxidant thioctic acid (alpha-lipoic acid) in symptomatic diabetic polyneuropathy, Diabetes Medicine, 1999


Lipoic acid improves distribution and metabolism of glucose in the body. Used as a supplement, lipoic acid may help with glucose absorption into muscle tissue and it may decrease the damaging effects on proteins of high glucose levels. Lipoic acid may also be helpful in improving blood flow in nerve tissue, we reduces stress from oxidation and therefore improve nerve conduction in diabetic neuropathy.

Two different randomized, double-blind, placebo-controlled trials have tested the effects of lipoic acid on diabetic neuropathy over a three week to four month period, resulting in improvement of symptoms in both trials.

Published: Ziegler D; Gries FA. Alpha-lipoic acid in the treatment of diabetic peripheral and cardiac autonomic neuropathy. Diabetes, 1997 Sep, 46 Suppl 2:, S62-63-61